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How Does PMDD Increase The Likelihood of Perinatal Depression?

by Samaira Farid,
Dr Jade Thomas
Medically reviewed by Dr Jade Thomas
Mother holding baby with gentle support, near window.
Bloume content relating to health, wellbeing and nutrition has been reviewed and validated by relevant medical professionals in the UK, based on UK guidelines and practices applicable at the time of publication. Recommendations in other localities may differ from those found on our site and you should always seek the guidance or advice of relevant healthcare professionals in your area.

If you have lived with Premenstrual Dysphoric Disorder (PMDD), you already know the particular weight of mood changes that arrive on a hormonal cue: the irritability that catches you off guard, the hopelessness that settles in during the late luteal phase, the tiredness that sits in you even when nothing else has changed. There is a meaningful link between PMDD and perinatal depression. If you have a PMDD history, you are more likely to develop depression during pregnancy and in the months after birth. Understanding that risk early gives you the best chance of building the right support around you.5

Why your PMDD history raises perinatal risk

Mental health difficulties during pregnancy and the first year after birth are common, affecting up to 1 in 5 women. These are different from the baby blues, a milder, short-lived low mood that usually lifts within two weeks of giving birth. If low mood, anxiety, or tearfulness sticks around past that point, or feels more intense, it is worth raising with your care team.6

How to recognise the warning signs

The symptoms of perinatal depression can look and feel a lot like what you already know from PMDD: mood swings, irritability, a sense of hopelessness, anxiety, and physical tiredness. Because none of this will feel entirely new to you, it can be harder to notice that something has shifted. The difference is the timing. These feelings are no longer tied to one phase of your cycle. If you notice low mood that lingers, a loss of interest, or anxiety that does not lift, those are signs to act on rather than wait out. This is not a checklist to diagnose yourself with, and a healthcare professional is the right person to make sense of what you are feeling.17

Woman in room, holding baby while crying.

Who to tell and when

Your mental health history is usually reviewed at your first midwife appointment, known as the booking appointment. This is your earliest and clearest chance to put your PMDD history on record. Tell your midwife and your GP. Be specific: describe how PMDD has affected you, how severe it has been, and whether you have had treatment. The more clearly your history is written down, the more easily your care team can set up a plan to keep an eye on things.8

If your PMDD has been severe or complex, a referral to a specialist perinatal mental health service may be worth considering. Not every experience of PMDD meets the threshold for that, but if your symptoms have had a real effect on your day-to-day life, it is reasonable to ask your midwife or GP whether a referral would suit you. These teams offer assessment and tailored support through pregnancy and after birth.9

If you are taking medication for PMDD

If you take an SSRI antidepressant for PMDD and find out you are pregnant, call your GP or psychiatrist urgently before you change anything. Stopping an SSRI suddenly carries a high risk of relapse, and it is not something to do without specialist guidance. Whether to stay on it, adjust it, or switch during pregnancy needs an individual assessment, so this is not something to sort out alone or in a rush. Your prescriber will weigh up the risks and benefits with you.10

What to ask for and how to advocate for yourself

Talking therapies, especially Cognitive Behavioural Therapy (CBT), a structured talking treatment that helps you work with unhelpful thought patterns, work well for perinatal mental health and are available through a GP referral. In England, you reach this through NHS Talking Therapies. Scotland, Wales, and Northern Ireland have their own equivalent services under different names, and your GP can point you to the local route. You do not need to wait until things feel severe to ask about a referral.2

If you raise your mental health history and feel your concerns are being brushed past, you are within your rights to ask for a second opinion. Any mention of a mental health difficulty should be explored carefully. Be clear: name your PMDD diagnosis, describe how it has affected you, and ask directly what monitoring or support is available to you.4

How to prepare for the perinatal period

Putting a plan in place before symptoms arrive tends to work better than scrambling once they do. A plan for the perinatal period might include regular movement, attention to your sleep, eating well, and stress-reduction techniques like mindfulness. These help your overall wellbeing, though they sit alongside clinical care rather than replace it if you are at higher risk.3

Building a support network matters too. Talking openly with your partner, close friends, or family about your PMDD history and what the perinatal period might hold for you can help the people around you notice changes and support you more easily. Antenatal classes are another way to connect with others expecting babies. Social support is an important part of the picture, alongside professional care.11

If you have a PMDD history and are pregnant or planning a pregnancy, raising it at your booking appointment is the single most practical step you can take. From that conversation, your care team can note your risk, talk through monitoring, and point you to any extra support available in your area.

Frequently Asked Questions

Sources

  • [1] PMDD

    The symptoms of perinatal depression can look and feel similar to PMDD

  • [2] Mental health

    Talking therapies, in particular Cognitive Behavioural Therapy (CBT), are an effective treatment for perinatal mental health conditions and are available through a GP referral, via NHS Talking Therapies in England.

  • [3] Mental health

    A wellness plan for the perinatal period can include regular physical activity, attention to sleep, a nutritious diet, and stress-reduction techniques such as mindfulness, as complementary strategies alongside clinical care.

  • [4] Seeking a second opinion

    If mental health concerns are not being taken seriously, you are within your rights to ask for a second opinion. Best practice in perinatal care treats any disclosure of mental health difficulty as something requiring careful exploration.

  • [5] Bidirectional link between premenstrual disorders and perinatal depression

    Research points to a meaningful link between PMDD and perinatal depression risk, with evidence suggesting that people with a PMDD history are significantly more likely to develop depression during pregnancy and in the postnatal period.

  • [6] Perinatal Mental Health Toolkit - RCGP

    Baby blues is a milder, transient low mood that typically resolves within two weeks of giving birth, distinct from perinatal depression.

  • [7] Mental health

    The symptoms of perinatal depression can look and feel similar to PMDD: mood swings, irritability, a sense of hopelessness, anxiety, and physical fatigue.

  • [8] Summary of NICE guidance on perinatal mental health

    UK guidance recommends that mental health history should be reviewed at the first midwife appointment (booking appointment), and this is the key opportunity to disclose a PMDD diagnosis.

  • [9] Mental health

    If PMDD has been severe or complex, guidelines indicate that a referral to a specialist perinatal mental health service may be appropriate.

  • [10] Perinatal Mental Health Toolkit - RCGP

    If you are taking an SSRI antidepressant for PMDD and find out you are pregnant, contact your GP or psychiatrist urgently before making any changes. Stopping SSRIs abruptly carries a high risk of relapse and is not recommended without specialist guidance.

  • [11] Mental health

    Building a support network, including talking with a partner, friends, and family, and connecting with other expectant parents through antenatal classes, is an important complement to professional care for perinatal mental health.